Multivariate Classification of Major Depressive Disorder Using the Effective Connectivity and Functional Connectivity
نویسندگان
چکیده
منابع مشابه
Multivariate Classification of Major Depressive Disorder Using the Effective Connectivity and Functional Connectivity
Major depressive disorder (MDD) is a mental disorder characterized by at least 2 weeks of low mood, which is present across most situations. Diagnosis of MDD using rest-state functional magnetic resonance imaging (fMRI) data faces many challenges due to the high dimensionality, small samples, noisy and individual variability. To our best knowledge, no studies aim at classification with effectiv...
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Understanding abnormal resting-state functional connectivity of distributed brain networks may aid in probing and targeting mechanisms involved in major depressive disorder (MDD). To date, few studies have used resting state functional magnetic resonance imaging (rs-fMRI) to attempt to discriminate individuals with MDD from individuals without MDD, and to our knowledge no investigations have ex...
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Resting-state fMRI (RS-fMRI) has become a useful tool to investigate the connectivity structure of mental health disorders. In the case of major depressive disorder (MDD), recent studies regarding the RS-fMRI have found abnormal connectivity in several regions of the brain, particularly in the default mode network (DMN). Thus, the relevance of the DMN to self-referential thoughts and rumination...
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BACKGROUND Numerous studies have demonstrated the higher-order functions of the cerebellum, including emotion regulation and cognitive processing, and have indicated that the cerebellum should therefore be included in the pathophysiological models of major depressive disorder. The aim of this study was to compare the resting-state functional connectivity of the cerebellum in adults with major d...
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BACKGROUND Major depressive disorder is associated with functional alterations in activity and resting-state connectivity of the extended medial frontal network. In this study we aimed to examine how task-related medial network activity and connectivity were affected in depression. METHODS 18 patients with major depressive disorder, aged 15- to 24-years-old, were matched with 19 healthy contr...
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ژورنال
عنوان ژورنال: Frontiers in Neuroscience
سال: 2018
ISSN: 1662-453X
DOI: 10.3389/fnins.2018.00038